Some of you have highlighted clues pertaining to mention of a company hinting GE but you should also pay attention to the "ANTEO manufactured products" section. I am of the opinion that the company would not just arbitrarily create products without market research and quite specifically the part relating to the area of biosepration.
1) Coupling a GFP capture protein onto magentic particles for the purification of GFP tagged proteins 2) Coupling antibodies to magentic particles for exosome purification.
It is very interesting that the company decided to mention this in the quarterly. You will find that purification of exosome has wide use in veterinary field one of which is to preserve optimal health of calves as cited.Possibly also hinting towards use in chromatography.
There are other set of clues which point towards GE albeit on simple googling.
However, without much excitement one must examine the validity of such information.
From Wikipedia The isolation and detection of exosomes has proven to be complicated.[1] Due to the complexity of body fluids, physical separation of exosomes from cells and similar-sized particles is challenging. On the other hand, since the diameter of exosomes is typically below 100 nm and because they have a low refractive index, exosomes are below the detection range of many currently used techniques. Often, functional as well as antigenic assays are applied to derive useful information from multiple exosomes. Well-known examples of assays to detect proteins in total populations of exosomes are mass spectrometry and Western blot. However, a limitation of these methods is that contaminants may be present that affect the information obtained from such assays. Preferably, information is derived from single exosomes. Relevant properties of exosomes to detect include size, density, morphology, composition, and zeta potential.[28] Flow cytometry is probably the most commonly applied optical method to detect exosomes in suspension. Nevertheless, the applicability of flow cytometry to detect single exosomes is still inadequate due to limited sensitivity and potential measurement artifacts such as swarm detection.[29] Other methods to detect single exosomes are atomic force microscopy, nanoparticle tracking analysis, Raman microspectroscopy, resistive pulse sensing, and transmission electron microscopy.[28] Microarrays are now being used to detect exosomes.[30]
Good Luck.
ADO Price at posting:
15.0¢ Sentiment: Hold Disclosure: Held
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