"Radicool Views"
Signs of ethylene glycol poisoning depend upon the time after ingestion.[6] Symptoms usually follow a three-step progression, although poisoned individuals will not always develop each stage.[7][8]
- Stage 1 (30 minutes to 12 hours) consists of neurological and gastrointestinal symptoms and looks similar to alcohol poisoning.[9] Poisoned individuals may appear to be intoxicated, dizzy, lacking coordination of muscle movements, drooling, depressed,[6] and have slurred speech, seizuring, abnormal eye movements, headaches, and confusion.[9] Irritation to the stomach may cause nausea and vomiting.[7] Also seen are excessive thirst and urination.[9] Over time, the body metabolizes ethylene glycol into other toxins.
- Stage 2 (12 to 36 hours) where signs of "alcohol" poisoning appear to resolve, underlying severe internal damage is still occurring.[9] An elevated heart rate, hyperventilation or increased breathing effort, and dehydration may start to develop, along with high blood pressure and metabolic acidosis.[9] These symptoms are a result of accumulation of organic acids formed by the metabolism of ethylene glycol. Additionally low calcium concentrations in the blood, overactive muscle reflexes, muscle spasms, QT interval prolongation, and congestive heart failure may occur. If untreated, death most commonly occurs during this period.[7]
"Radicool Views" Signs of ethylene glycol poisoning depend upon...
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