I would recommend trying to avoid DOMS, as there is very little...

I would recommend trying to avoid DOMS, as there is very little connection between DOMS and progression for trained athletes. There is a connection, however, between progressively increasing volume over time and stimulating unique growth/adaptation responses with different loads/volumes (e.g. rep ranges and weight). If you want to build strength, then the majority of your workouts should be low RM.

Any of the large rear chain movements are individual and contextually specific. Tillett is right about risk/reward for deadlifting patterns, but they provide substantial benefit for strength and development. The way that I include them into a phasic plan is on a 6- or 12-week basis (e.g. in for 6-weeks, out for 6-weeks), volume is always relative to capacity but sets are low (max 2 sets), and manage other large compound movements with similar hinging patterns.

For those of you that have recurrent back pain, piriformis syndrome is something that comes up frequently amongst clients that spend a lot of time in the office. It's where the sciatic nerve becomes trapped between the piriformis and the hip bone. I highly recommend incorporating daily stretching of the piriformis through proprioceptive neuromuscular facilitation (PNF) during periods of inflammation. Afterward, continue with PNF only when symptoms arise. PNF can be pretty uncomfortable, though it is a highly effective and far better than traditional stretching methods.