Just as an aside to both of the articles linked here - these both indicate that overexpression of FTO was
correlated to positive therapeutic outcomes (in this case improved cardiac/cardiocyte function and oxidative stress reduction/protection)
I.e this is a case (like many) where overexpressing FTO results in positive outcomes, rather than negative such as Zantrene’s current use cases as an inhibitor.
Full disclosure that I’m a massive RAC supporter, just important to remember to distinguish between FTO over/under expression therapeutic targets, as to not cross lines on where Zantrene is helpful and where it’s probably going to worsen the indication, like in the cases above.
Interestingly the first article speaks to high levels FTO improving cardiac protection in the case of a heart attack/cardiac infarction (blocked blood vessels). This runs contrary to FTO inhibition being the opposite scenarioo than above, resulting in cardiac protection in the presence of chemotherapeutics. Clearly m6a transcriptions is incredibly specific therapeutically when changing your eraser/writer/reader levels, fascinated to see where Race’s m6a artillery ends up in Pillar 3.
General Comments / Chat, page-6070
-
-
- There are more pages in this discussion • 4,977 more messages in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add RAC (ASX) to my watchlist
|
|||||
Last
$1.65 |
Change
-0.095(5.44%) |
Mkt cap ! $281.0M |
Open | High | Low | Value | Volume |
$1.78 | $1.78 | $1.62 | $285.9K | 170.1K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
1 | 16759 | $1.65 |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
$1.69 | 12047 | 1 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
1 | 16759 | 1.650 |
1 | 5000 | 1.640 |
1 | 1000 | 1.635 |
1 | 10000 | 1.630 |
5 | 12118 | 1.600 |
Price($) | Vol. | No. |
---|---|---|
1.690 | 12047 | 1 |
1.720 | 2604 | 1 |
1.770 | 2332 | 1 |
1.780 | 586 | 1 |
1.820 | 9999 | 1 |
Last trade - 16.10pm 03/07/2024 (20 minute delay) ? |
Featured News
RAC (ASX) Chart |
The Watchlist
TON
TRITON MINERALS LTD
Adrian Costello, Executive Director
Adrian Costello
Executive Director
Previous Video
Next Video
SPONSORED BY The Market Online