Just as an aside to both of the articles linked here - these...

Just as an aside to both of the articles linked here - these both indicate that overexpression of FTO was
correlated to positive therapeutic outcomes (in this case improved cardiac/cardiocyte function and oxidative stress reduction/protection)

I.e this is a case (like many) where overexpressing FTO results in positive outcomes, rather than negative such as Zantrene’s current use cases as an inhibitor.

Full disclosure that I’m a massive RAC supporter, just important to remember to distinguish between FTO over/under expression therapeutic targets, as to not cross lines on where Zantrene is helpful and where it’s probably going to worsen the indication, like in the cases above.

Interestingly the first article speaks to high levels FTO improving cardiac protection in the case of a heart attack/cardiac infarction (blocked blood vessels). This runs contrary to FTO inhibition being the opposite scenarioo than above, resulting in cardiac protection in the presence of chemotherapeutics. Clearly m6a transcriptions is incredibly specific therapeutically when changing your eraser/writer/reader levels, fascinated to see where Race’s m6a artillery ends up in Pillar 3.