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    Borje and the Anderssen Centre in US completed pre-clinical YEARS AGO showing synergy in combination. Way before COH.. It just took ages to publish the data prior to being able to commence Naglar 2.... Therefore, the objective for Sheba 2 was to get the combination into the clinic and progress Zantrene.

    Paeds R/R AML and PRV was initially single agent from memory??
 
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