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    Great question @good1234 drug pricing seems like it would be simple, if I can give some reading that helped me a little.

    Keys are a number of factors that would see R220 priced multiples higher than original central line formula. Triangle report delved into the pharmacoeconomics (delve into this word/world as a start) with why & how Bisantrene could be priced.

    Remember the extremely high cost of healthcare in the USA, where a car accident can bankrupt someone.

    The graph below is often used in terms of drug pricing. While a new drug may be more expensive the payers (insurance companies & patients) will be willing to pay more if the drug is a. more effective & B. Improves Quality Adjusted Life Years (QALYs).

    For R220 we are looking at:
    • Better improved formula, quality.
    • Easier method of delivery. Costs hospitals/insurance & patients less than central line.
    • MOD leads to better patient quality of life. Less risk of infections & follow up hospital visits.
    • Less side effects such as damage to veins/arteries (reason others delivered as central line?)

    https://hotcopper.com.au/data/attachments/5459/5459140-4e20776413025cd686c0bf82faf3ee53.jpg


    Below is slightly off the topic of actual pricing, but a rabbit hole worth exploring.
    Paper by Nature included as well.

    https://hotcopper.com.au/data/attachments/5459/5459121-e99883fcb78723e2cda9be207a788663.jpg


    The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology. https://www.nature.com/articles/s41523-020-00193-6

 
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