Great question @good1234 drug pricing seems like it would be simple, if I can give some reading that helped me a little.
Keys are a number of factors that would see R220 priced multiples higher than original central line formula. Triangle report delved into the pharmacoeconomics (delve into this word/world as a start) with why & how Bisantrene could be priced.
Remember the extremely high cost of healthcare in the USA, where a car accident can bankrupt someone.
The graph below is often used in terms of drug pricing. While a new drug may be more expensive the payers (insurance companies & patients) will be willing to pay more if the drug is a. more effective & B. Improves Quality Adjusted Life Years (QALYs).
For R220 we are looking at:
- Better improved formula, quality.
- Easier method of delivery. Costs hospitals/insurance & patients less than central line.
- MOD leads to better patient quality of life. Less risk of infections & follow up hospital visits.
- Less side effects such as damage to veins/arteries (reason others delivered as central line?)
Below is slightly off the topic of actual pricing, but a rabbit hole worth exploring.
Paper by Nature included as well.
The quality of life index: a pilot study integrating treatment efficacy and quality of life in oncology. https://www.nature.com/articles/s41523-020-00193-6
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