Percentages
200% for both, provided only that there is no technical stuff-up such as mislabelling vials, dropping glassware containing blood samples on the floor, accidentally swapping an orange drink for bisantrene, etc.
Why?
FTO inhibition
COH preclinical has been replicated at Univ of Chicago.
Historical clinical trials show unexplained efficacy at low doses.
Dominissini would have told RAC if FTO was NOT inhibited at Sheba, and RAC would have been obliged to announce it.
Cardioprotection
Mouse hearts are good models for human hearts.
Human heart cells in vitro were protected. Why would human heart cells in situ behave differently?
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