Whats Nagler trying to prove out using heavily pretreated patients that have received many lines of treatment?
Is he using patients with no other option for Bisantrene and other more promising treatments for those with fewer lines? *I noted a video of Nagler praising up how good CarT was for AML. Are these patients getting preference to the earlier line of treatments as Nags thinks it's a better option?
Is Nags deliberately using end of the line patients because he has confidence in the treatment combo?
How is he meant to prove dosing if X amount die?
I just thought it'd be better to have patients similar to Sheba 1 with few lines to get a more even gauge of progressing Bis. How many PoC trials are needed to prove a drug like Bis out. Back to the start with R220?
I have no idea. Just thinking
BTW everyone JDP has already explained we have at least 20% bridged
https://hotcopper.com.au/posts/70552430/single
Whats Nagler trying to prove out using heavily pretreated...
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