Thanks Stezza although I am not sure it was good for me as ‘real life’ had put me into a bit of a cortisol high leading to that fast ‘wing’ over EBR (during which I’ve enjoyed multiple discoveries on a new interest in a short time…. Which actually was/will be ‘good’ )
Re size of standard (medical?) study groups, I am no authority and have no answer except;
Maybe it depends?
In support of this, I note the July 31, 2023 paper clarifies that
“The first patient was enrolled in SOLVE-CRT in January 2018. Enrollment was severely impacted by the COVID-19 pandemic and was paused in March 2020 after 108 patients were enrolled. At that time, the investigators worked with the US Food and Drug Administration (FDA) to revise the clinical protocol, implementing a single-arm nonrandomized part to complete the study.”
cheers
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