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http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=%2Fnetahtml%2FPTO%2Fsearch-adv.htm&r=1&f=G&l=50&d=PTXT&p=1&p=1&S1=(%22Bionomics+Limited%22.ASNM.)&OS=an/"Bionomics+Limited"&RS=AN/"Bionomics+Limited"

United States Patent 7,667,028
Kremmidiotis , et al.
February 23, 2010


Compositions and methods for angiogenesis-related molecules and treatments


Abstract
Short interfering RNA (siRNA) molecules which modulate the expression of an angiogenesis-related gene by RNA interference are described. Short hairpin RNA (shRNA) molecules comprising said siRNA molecules are also described. These molecules can target all, or specific, isoforms of the gene. The use of these molecules and of isoforms of the gene for the treatment and diagnosis of angiogenesis-related disorders is also described.



Inventors: Kremmidiotis; Gabriel (Flagstaff Hill, AU), Lavranos; Tina Christine (Colonel Light Gardens, AU), Leske; Annabell Frances (Allenby Gardens, AU)

Assignee: Bionomics Limited (Thebarton, AU)