Great spot, gmutton.So, August 24, 2023 we learned OPT was about...

Great spot, gmutton.

So, August 24, 2023 we learned OPT was about 75% enrolled (with COAST running slightly ahead of ShORe)

Now, supposedly on the Eyecelerator Forum held November 2, 2023 during the AAO Meeting 2023, OPT says they are about 80% enrolled.

The rate of enrollment having been about 5 percentage points within 10 weeks.


Now looking forward:

A) Base Case, assuming OPT continues at current pace of enrollment:
85% enrollment by January 11, 2024
90% enrollment by March 21, 2024
95% enrollment by May 30, 2024 (that‘s when COAST could be reported fully enrolled)
100% enrollment by August 8, 2024 (ShORe being fully enrolled as well)

B) Bull Case, assuming OPT accelerates the 5% enrollment time by 1 week after each 5% patient package:
85% enrollment 9 weeks later, that‘s by January 4, 2024
90% enrollment 8 weeks later, that‘s by February 29, 2024
95% enrollment 7 weeks later, that‘s by April 18, 2024 (that‘s when COAST could be reported fully enrolled)
100% enrollment 6 weeks later, that‘s by May 30, 2024 (ShORe being fully enrolled as well)

In any case, the latest guidance given August 24, 2023 with COAST being fully enrolled by Q1 2024 and ShORe by Q2 2024 does not feel overly conservative. All the opposite…