my understanding is that zanamivir/relenza does have less side effects, and is safer to use in pregnancy than oseltamivir/tamiflu. however zanamivir is currently only available as an inhaler.
just read a 2009 article saying WHO recently revealed that 39% of the world's H1N1 influenza A virus isolates were resistant to oseltamivir. despite that protocol is to give suspected cases of swine flu tamiflu (at least in wa)
not exactly sure what poly was trying to prove with that article; NI's came into prominence because of the pandemic that is swine flu and earlier because of SARS, and the authors agreed with this in their conclusion.
the 2009 article I mentioned earlier found that for susceptible influenza A/H1N1 (swine flu) isolates, zanamivir is not statistically significantly better than tamiflu. But for oseltamivir-resistant influenza A/H1N1, zanamivir was indicated.
Other findings: For influenza B, zanamivir was found to be more effective For influenza A/H3N2, oseltamivir was found to be more effective.
BTA Price at posting:
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