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how simular are mice to humans

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    Obviously like many on here have been thinking about AHZ a bit and the big question for me right now is trying to figure out what the answer is going to be regarding the HSV (Herpes Phase 1 Trial)Now we all know its safe the question is the immune response.

    Like I said on here earlier I found an article about some Larry who had come up with a vaccine but it killed the mice so we are one big step up on that with human trials going safely.

    Found this amongst other articles when thinking about how similar a mouse is to humans when it comes to testing and trials for anyone who is interested. But haven't found any percentages or numbers showing successful trials on mice not working on humans.

    http://www.biomedcentral.com/content/pdf/1471-2105-14-S6-S3.pdf

    "The mouse is the primary mammalian model used in
    the study of vaccine candidates including those against
    Brucella
    species [8]. Mice are genetically similar to
    humans with similar immune defenses and physiological
    mechanisms. The mouse genome sequence is available
    and has been well studied compared to other animal mod-
    els. One critical issue to consider with vaccine animal stu-
    dies is that many variables (e.g., vaccine doses, vaccination
    routes, and mouse strains and ages) can affect"


 
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