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human clinical trial successful

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    Sydney - Thursday - December 7: (RWE Australian Business News) -
    OBJ Ltd (ASX code: OBJ) today announced the successful completion of the
    second phase of the company's human clinical trial into the enhanced
    transdermal delivery of the local anaesthetic Ametop, which uses
    Tetracaine as its active ingredient.
    The combined results of this study and the earlier April study
    show that Dermaportation was able to induce numbness in volunteer
    subjects within 20 minutes using one-fifth of the recommended drug
    dosage. This represents a significant reduction in both the amount of
    drug required and the time to onset compared with manufacturer's
    recommended times of 30 to 45 minutes.
    At 20 minutes after drug administration, there were
    statistically significant differences in the touch-sensitivity between
    active and placebo treatment areas in volunteers.
    This provides evidence of successful enhanced skin penetration
    of tetracaine under the influence of Dermaportation.
    A single volunteer study was run in parallel, using 15-minute
    Dermaportation and drug contact time, which produced greater numbness
    than the control. This suggests that the Dermaportation technology may
    be effective in even less time than used in the study.
 
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