Some early observations on the NEJM "study"
Uh...this "study" relied on people self-reporting symptoms over a website. No actual MD visits. No tests run. No viral loads measured. Very odd study design. Meanwhile, India found a strong, dose-dependent reduction in covid risk with PREP admin of HCQ
Small data and young patients. Time to move on. Next study. Appreciate the effort but nothing to really see here.
Meanwhile a far more reputable Indian study is ignored by the MSM. It reported
Consumption of four or more maintenance doses of HCQ was associated with a significant decline in the odds of getting infected (AOR: 0.44; 95% CI: 0.22-0.88); a dose-response relationship existed between frequency of exposure to HCQ and such reductions (χ2 for trend=48.88; P<0.001). In addition, the use of PPE was independently associated with the reduction in odds of getting infected with SARS-CoV-2. Interpretations & conclusions: Until results of clinical trials for HCQ prophylaxis become available, this study provides actionable information for policymakers to protect HCWs at the forefront of COVID-19 response. The public health message of sustained intake of HCQ prophylaxis as well as appropriate PPE use need to be considered in conjunction with risk homoeostasis operating at individual levels.
http://www.ijmr.org.in/preprintarticle.asp?id=285520;type=0
So strange that studies reporting successful use of HCQ get ignored but dodgy unsuccessful studies are so widely acclaimed.
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