Just as there are sometimes outliers in the placebo group there are some times outliers in the drug group. I remember, for instance, several people who said gammagard had produced significant changes in their loved ones. It is possible that people were misdiagnosed or that they metabolized the drug differently, but neither seems likely. It is important to get to the bottom of why some people in the placebo group did better than other people in the placebo group and why some people in the drug group did better than other people in the drug group. There are certain drugs that only treat symptoms of Alzheimer's disease (such as acetylcholinesterases and anti-amyloid plaque medications) and there are certain drugs that intervene in the disease process (namenda and pbt2) but probably not well enough unless further altered.
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