Important milestone: 90% enrollment achieved, timeline confirmed!, page-10

6 letters improvement in BCVA is a random number I picked to define the „strongest positive P3 outcome imaginable“. The color of the sky not being able to turn „more blue“ than in such an „absolute blue sky scenaro“, as I would describe it. In other words, a result beyond which even the most aggressive peak sales estimates would not increase further. The entire professional world in ophthalmology already having fallen to their knees and praising OPT‘s glory night and day.

Of course, as you very rightfully pointed out to, 4 or 5 letters are a much more probable outcome in case of both drug arms showing a statistically meaningful improvement in BCVA at topline readout.