imu bird flu success

WHAT WILL A SUCCESSFUL IMUGENE VACCINE MEAN?

Well in terms of viability it will be enourmous because there is no cost effective method of protecting poultry in h5n1 affeted areas.

Vaccines exist however it is cheaper for farmers to kill their entire flock than to vaccinate their flocks with the current h5n1 subcutaneous vaccine which needs to be administered twice in a broilers short life of 42 days.

imugene have a proven,tested and medically accredited delivery method to do this. The ADENOVIRUS DELIVERY PLATFORM.

Once the correct protective genes are identified and inserted in the synthetic genes I suspect that a adequate immune response ill be achieved.

What will it do to the Share price is the question I ask?
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Dr Warwick Lamb, Managing Director of Imugene. “The gene used is the correct protective gene and once we get correct expression of this gene, we expect effective protection against the Avian Influenza.”
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The research will utilise Imugene's Adenoviral Vector Delivery System (AVDS) - which originated from CSIRO research - to deliver a small portion of the flu genetic material to poultry to stimulate the birds' immune response and provide protection from the flu virus.

Imugene's Managing Director, Dr Warwick Lamb, says the platform AVDS allows a new potential vaccine to be constructed quickly at CSIRO's Australian Animal Health Laboratory (AAHL) in Geelong - one of the world's leading animal disease diagnosis and research facilities.

"The CSIRO research team have been working with the AVDS and its use with poultry for over a decade and have relevant experience with chicken viruses," Dr Lamb says.

"Vaccines based on the AVDS only use a portion of the viral structure of the flu virus, making them safer than a live attenuated vaccine approach. With the latter approach, there is some risk that the vaccine could mutate or combine with naturally occurring influenza virus, resulting in potential new strains that are not covered by the existing vaccines. The AVDS vaccine would avoid this problem."
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Developing an effective vaccine against the current bird flu is a priority
for Imugene. The vaccine under development has major advantages
- safety and ability to be used on a mass scale as the vaccine can be
delivered through water or feed. Trials are underway to determine
the dosage to achieve the most effective antibody response.
Different vaccines are under development for broilers and
layers/breeders.