Yes but she relapsed afterward which is why this is a case study...

  1. 30,642 Posts.
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    Yes but she relapsed afterward which is why this is a case study for CHECKvacc, there is mentioned of pseudo progression for CF33 as seen in the VAXINIA clinical trial so similar to what was observed.

    "However, despite anti-tumor response after sequential treatment with CHECKvacc and T-DXd, the subject experienced relapse after 10 months of PFS"

    "To date, no CR in a patient with HER2-zero metastatic BC receiving T-DXd has been reported. In the DESTINY-Breast04 trial targeting HER-2 low BC, only 3.6% of patients in the T-DXd group achieved CR. 15 No patients achieved CR in the HER2-zero cohort of the DAISY trial, although this could be due to limited sample size (N = 37)"
 
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