Would paxalisib be a great treatment option here? Potentially, as it has a safe side effect profile and is a potent inhibitor of the PI3K/Akt/mTOR Pathway.
https://www.mdpi.com/1999-4923/13/8/1195/htm
Inhibitors of the PI3K/Akt/mTOR Pathway in Prostate Cancer Chemoprevention and Intervention
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