RCE recce pharmaceuticals ltd

0.00%

30.5¢

BobF, don't forget about R435, which is a variant of R327 aimed...

First 47 Last

Share
Profile

Follow
bcr

5,637 Posts.

132

09/05/24

23:56

Post #: 73753071
Share

Originally posted by BobF ↑

Interesting ideas, yes, but I do not see any evidence you have provided for your assertions.

My reading of the trial results does indicate that the compound is excreted very rapidly irrespective of how the product is administered. Naturally it would be most convenient to take a pill to get the drug to ist site of action, but it does seem to be processed quite quickly. It may not be the most desirable feature of it, but that is what it does. I would particularly like to see evidence for there being no impact on the gut as suggested. If it is taken orally the concentrations in the gut will be large, and until it is absorbed it will kill whatever lives in the gut that is vulnerable to the drug at those levels. It does sound like it is pretty lethal for most bugs, and that would include gut bacteria I presume. In the interview this is also suggested to be a fairly significant consideration. So show me evidential proof that that does not happen, and if it does happen then how much. The poison is in the dose I think.

Once it is absorbed into the blood yes it will begin to be excreted and metabolised. IV delivery is used to get it into the blood, and from there to the kidneys and bladder. In being excreted from the kidneys to the bladder it appears to have been shown to kill the organisms responsible for urosepsis fairly quickly. If it is metabolised to an inactive compound I have not seen any information on that, and yes that could be significant. I would therefore welcome that info being posted or linked to. I noted that when the compound is dispensed into the bladder by catheter it is there very effective, If so then that is surely important and beneficial. If it kills them quick then they are dead quick, and a high concentration does not need to be maintained for long to kill them all deader. As I read it, that is the claim. If that is not the case please explain why the trials are being accepted as valid by the profession and funders.

I take it from your referring to R327 as 'swamp juice' and 'magic pixie fluid' that you do not believe it to be beneficial or effective. May I then ask why you show your disclosure status as 'held'. Why on earth do you continue to hold?

Expand

BobF, don't forget about R435, which is a variant of R327 aimed specifically at oral administration.

The efficacy study was conducted by an independent Contract Research Organization to assess oral dose-dependent efficacy of RECCE^® 435 in-vivo (rats) against a clinical isolate of H. pylori. H. pylori is a species of Gram-negative bacteria commonly infecting the lining of the stomach and upper digestive tract.

Expand

Source: https://finance.yahoo.com/news/recce-pharmaceuticals-announces-positive-oral-120000992.html

So, over four years ago, they split off oral dosage into a different development path, so that it will not interrupt development of the flagship product R327, which is aimed at IV administration targeting sepsis in the blood. That is it's primary goal.

They also created R529, for the same purpose; to not hold up development of R327, yet allow for specifically targeting viral infections.

Both variants as far as I understand, take a much lower priority to R327 and quite rightly so.

Last edited by bcr: 09/05/24

RCE Price at posting: 65.0¢ Sentiment: Hold Disclosure: Held
5 Upvote

0 Great analysis

Reply

Top Stories

PH2

Iran, nuclear energy, oil – a revival for hydrogen! Nel ASA, Pure Hydrogen, Plug Power, and Oklo

ASM

'Encouraging' signs as ASM puts cash-saving options to test at Dubbo drill site

BBT

'Clearly superior': Betr doesn't want to accept PointsBet picking Mixi instead

Listen: HotCopper Wire Podcast 013 - They changed the IPO rules (and that's a good thing)

DYL

Much-shorted Oz Uranium stocks enjoying big week – and big price jumps

First 47 Last

Add to My Watchlist

What is My Watchlist?

A personalised tool to help users track selected stocks. Delivering real-time notifications on price updates, announcements, and performance stats on each to help make informed investment decisions.

(20min delay)
Last 30.5¢		Change 0.000(0.00%)		Mkt cap ! $87.95M

Open	High	Low	Value	Volume
30.5¢	31.0¢	30.0¢	$12.86K	42.12K

Buyers (Bids)

No.	Vol.	Price($)
1	17251	30.5¢

Sellers (Offers)

Price($)	Vol.	No.
31.5¢	2783	3

View Market Depth

No.	Vol.	Price($)
1	17251	0.305
6	31657	0.300
2	5523	0.295
9	149533	0.290
2	135000	0.285

Price($)	Vol.	No.
0.315	2783	3
0.320	4662	4
0.325	2257	2
0.330	25000	1
0.350	30000	2

Last trade - 12.07pm 17/06/2025 (20 minute delay)

RCE (ASX) Chart

BobF, don't forget about R435, which is a variant of R327 aimed...

Iran, nuclear energy, oil – a revival for hydrogen! Nel ASA, Pure Hydrogen, Plug Power, and Oklo

'Encouraging' signs as ASM puts cash-saving options to test at Dubbo drill site

'Clearly superior': Betr doesn't want to accept PointsBet picking Mixi instead

Listen: HotCopper Wire Podcast 013 - They changed the IPO rules (and that's a good thing)

Much-shorted Oz Uranium stocks enjoying big week – and big price jumps

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News

BobF, don't forget about R435, which is a variant of R327 aimed...

Top Stories

Iran, nuclear energy, oil – a revival for hydrogen! Nel ASA, Pure Hydrogen, Plug Power, and Oklo

'Encouraging' signs as ASM puts cash-saving options to test at Dubbo drill site

'Clearly superior': Betr doesn't want to accept PointsBet picking Mixi instead

Listen: HotCopper Wire Podcast 013 - They changed the IPO rules (and that's a good thing)

Much-shorted Oz Uranium stocks enjoying big week – and big price jumps

Featured News

Buyers (Bids)

Sellers (Offers)

Featured News