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''People who were vaccinated against COVID-19 before getting infected had a significantly lower risk of developing long COVID compared to those who were unvaccinated.
[1] The study found that approximately 27% of unvaccinated COVID-19 cases experienced long COVID symptoms at 90 days post-infection, compared to only 8% of vaccinated cases (relative risk 0.31). Vaccinated cases also reported less severe long COVID symptoms.
[2] Another large study estimated that a single pre-infection vaccine dose reduces the risk of long COVID by 21%, two doses by 59%, and three or more doses by 73% compared to unvaccinated individuals.
[3] While the risk of long COVID exists even in young adults, getting two doses of the COVID-19 vaccine is highlighted as one of the best ways to protect against developing long COVID symptoms.
[4] This study found no difference in long COVID incidence based on vaccination status, but had a small unvaccinated sample, limiting conclusions on vaccine effectiveness against long COVID.
[5] In a Pakistani study, lack of vaccination was found to be an independent predictor of long COVID, with unvaccinated patients having 2.42 times higher odds of developing long COVID compared to vaccinated patients after adjusting for other factors.
In summary, multiple studies consistently show that being vaccinated against COVID-19, especially with multiple doses before infection, significantly reduces the risk and severity of developing long COVID symptoms compared to unvaccinated individuals.[1][2][3][5]
Citations:
[1] https://academic.oup.com/ofid/article/11/2/ofae039/7585852
[2] https://time.com/6338434/vaccination-long-covid-risk/
[3] https://sbuhb.nhs.wales/news/vaccin...ong-covid-risk-if-they-do-not-get-vaccinated/
[4] https://www.nature.com/articles/s41598-023-50024-4
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664948/