Is this the 4-HPR preclinical which you looked at?
Nuclear Transport Inhibitor That Modulates the Unfolded Protein Response and Provides In Vivo Protection Against Lethal Dengue virus Infection
Johanna E. Fraser, Satoru Watanabe, Chunxiao Wang, Wing Ki Kitti Chan, Belinda Maher, Adam Lopez-Denman, Caroline Hick, Kylie M. Wagstaff, Jason M. Mackenzie, Patrick M. Sexton ... Show more
The Journal of Infectious Diseases, Volume 210, Issue 11, 1 December 2014, Pages 1780–1791,
https://academic.oup.com/jid/article/210/11/1780/2908496
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The article is dated 2014.
So it's taken seven years for not much to happen.
At least P1 can be skipped.
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