Garnev, from my understanding TPM is not ‘Phospha E’ but a drug...

Garnev, from my understanding TPM is not ‘Phospha E’ but a drug delivery system

Phospha-E is patented vitamin E product, for use as a nutritional product in the prevention and treatment of metabolic syndrome.

Transdermal Penetration Matrix is a transdermal delivery system or a method of applying a drug to unbroken skin. The drug is absorbed through the skin and enters the body’s systems.
Transdermal patch (skin patch) is used to deliver a controlled dose of a drug through the skin over a period of time. A skin patch uses a special membrane to control the rate at which the liquid drug contained in the reservoir within the patch can pass through the skin and into the bloodstream. Some drugs must be combined with substances, such as alcohol, that increase their ability to penetrate the skin in order to be used in a skin patch.

As to POH’s Oxycodone/TPM Patch, it is a trial of proving that Oxycodone could be delivered through TPM.

“Oxycodone is an opioid analgesic medication synthesized from opium-derived thebaine. It was developed in 1916 in Germany, as one of several new semi-synthetic opioids in an attempt to improve on the existing opiates and opioids: morphine, diacetylmorphine (heroin), and codeine. Currently it is best known as the main active ingredient in a number of oral medications commonly prescribed for the relief of moderate to severe pain”(definition from wikipedia)

THE MEDICAL NEWS
from News-Medical.Net - Latest Medical News and Research from Around the World

Phosphagenics commences Phase 1B clinical trial of its oxycodone/TPM transdermal patch systems

http://www.news-medical.net/news/20091202/Phosphagenics-commences-Phase-1B-clinical-trial-of-its-oxycodoneTPM-transdermal-patch-systems.aspx

First subject dosed in phase Ib of Phosphagenics' Oxycodone Patch
http://www.biospectrumasia.com/content/021209AUS11424.asp