Its Over, page-341

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    Biotron(BIT) successful Phase 2 Clinical trial for HIV-1 treatment explained:

    “As we have always maintained, eradication of this virus population fromthese reservoirs is central to an

    eventual HIV1 cure.

    This important trial builds on a solid foundation of previously reportedlaboratory studies that showed

    that BIT225 attacks HIV1 in macrophage cells that current drugs cannotaccess.

    Unless macrophage cells are cleared of HIV1 virus, a cure is notpossible. Current drugs do an excellent job

    of taking HIV1 in the blood to undetectablelevels but do not clear virus in macrophages

    These cells, whichreside in the body’s tissues, produce low levelsof HIV1, even in patients taking current antiretroviral drugs

    This means that the infection persists. Patients can’t stop takingantiretroviral drugs; if they do, the virus

    quickly rebounds to high levels

    Clearing out virusfrom these macrophage reservoir cells is an important key step towardseradicating HIV1 completely.

    Biotron’s data indicate that BIT225 could form part of a cure strategyfor HIV1 infection.

    The clinical trial also showed that BIT225 reduced an importantmacrophage associated protein (sCD163)

    that correlates with severity of disease….”

    Incoming weeks, Biotron will brief potential pharmaceutical partners on the trialoutcomes.

    We believethat the successful results from this study will facilitate commercialisationnegotiations with these parties

    In parallel, the Company expects to present the detailed data from theclinical trial at conferences in late 2018/early 2019


    The downdraft is being felt across small/microcaps today. Being ahead of the curve helped saved 5.9% in returns compared against 'doing nothing" and holding onto all positions and this also assumed that the current loss position in BIT was not entered into.


    COVERAGE DATE STOCKSPRICE ON COVERAGE DATEPRICE @MIDDAYGAIN%
    3/10BIT $          0.140  $      0.122 -12.9%
    26/9CXL $          0.735  $      0.750 2.0%
    20/9-close4DS $          0.064  $      0.066 3.1%
    3/9NST $          8.140  $      8.450 3.8%
    29/8-closeSVA $          0.037  $      0.035 -5.4%
    20/8-closeNGI $          5.810  $      5.160 -11.2%
    8/8-closeSFC $        15.050  $    16.470 9.4%
    6/8-closeCGL $          7.080  $      7.930 12.0%
    31/7-closeMYE $          1.180  $      1.435 21.6%
    30/7-closeMP1 $          4.370  $      3.990 -8.7%
    26/7-closeSKF $          0.150  $      0.200 33.3%
    24/7ZEN $          1.060  $      0.790 -25.5%
    23/7-closeCXL $          0.630  $      0.830 31.7%
    17/7COE $          0.445  $      0.465 4.5%
    13/7-closeSHL $        26.500  $    25.360 -4.3%
    29/6BYE $          0.340  $      0.350 2.9%
    28/6-closeATC $          0.195  $      0.140 -28.2%
    18/6-closeA2M $        10.780  $    11.490 6.6%
    18/6-closeCGC $          8.750  $      7.240 -17.3%
    14/6-closeNZK $          2.240  $      2.480 10.7%
    4/6-closeBUB $          0.830  $      0.625 -24.7%
    15/5-closeSW1 $          0.410  $      0.380 -7.3%
    14/5-closeRHC $        65.420  $    55.250 -15.5%
    9/5-closeFYI $          0.145  $      0.115 -20.7%
    3/5-close4DS $          0.057  $      0.100 75.4%
    2/5-closePME $          8.150  $    10.860 33.3%
    1/5TTT $          1.540  $      1.590 3.2%
    30/4-closeCTD $        24.880  $    33.540 34.8%
    18/4-closeCLV $          1.030  $      1.575 52.9%
    18/4-closeVIV $          0.054  $      0.043 -20.4%
    11/4-closeAPX $          8.820  $    15.010 70.2%
    11/4-closeBHP $        29.440  $    32.385 10.0%
    11/4-closePPS $          0.595  $      1.135 90.8%
    11/4PTB $          0.545  $      0.625 14.7%
    Return @9.53%assuming @ $1k even per stock




 
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