Biotron(BIT) successful Phase 2 Clinical trial for HIV-1 treatment explained:
“As we have always maintained, eradication of this virus population fromthese reservoirs is central to an
eventual HIV1 cure.
This important trial builds on a solid foundation of previously reportedlaboratory studies that showed
that BIT225 attacks HIV1 in macrophage cells that current drugs cannotaccess.
Unless macrophage cells are cleared of HIV1 virus, a cure is notpossible. Current drugs do an excellent job
of taking HIV1 in the blood to undetectablelevels but do not clear virus in macrophagesThese cells, whichreside in the body’s tissues, produce low levelsof HIV1, even in patients taking current antiretroviral drugs
This means that the infection persists. Patients can’t stop takingantiretroviral drugs; if they do, the virus
quickly rebounds to high levelsClearing out virusfrom these macrophage reservoir cells is an important key step towardseradicating HIV1 completely.
Biotron’s data indicate that BIT225 could form part of a cure strategyfor HIV1 infection.
The clinical trial also showed that BIT225 reduced an importantmacrophage associated protein (sCD163)
that correlates with severity of disease….”
Incoming weeks, Biotron will brief potential pharmaceutical partners on the trialoutcomes.We believethat the successful results from this study will facilitate commercialisationnegotiations with these parties
In parallel, the Company expects to present the detailed data from theclinical trial at conferences in late 2018/early 2019
The downdraft is being felt across small/microcaps today. Being ahead of the curve helped saved 5.9% in returns compared against 'doing nothing" and holding onto all positions and this also assumed that the current loss position in BIT was not entered into.
COVERAGE DATE STOCKS PRICE ON COVERAGE DATE PRICE @MIDDAY GAIN% 3/10 BIT $ 0.140 $ 0.122 -12.9% 26/9 CXL $ 0.735 $ 0.750 2.0% 20/9-close 4DS $ 0.064 $ 0.066 3.1% 3/9 NST $ 8.140 $ 8.450 3.8% 29/8-close SVA $ 0.037 $ 0.035 -5.4% 20/8-close NGI $ 5.810 $ 5.160 -11.2% 8/8-close SFC $ 15.050 $ 16.470 9.4% 6/8-close CGL $ 7.080 $ 7.930 12.0% 31/7-close MYE $ 1.180 $ 1.435 21.6% 30/7-close MP1 $ 4.370 $ 3.990 -8.7% 26/7-close SKF $ 0.150 $ 0.200 33.3% 24/7 ZEN $ 1.060 $ 0.790 -25.5% 23/7-close CXL $ 0.630 $ 0.830 31.7% 17/7 COE $ 0.445 $ 0.465 4.5% 13/7-close SHL $ 26.500 $ 25.360 -4.3% 29/6 BYE $ 0.340 $ 0.350 2.9% 28/6-close ATC $ 0.195 $ 0.140 -28.2% 18/6-close A2M $ 10.780 $ 11.490 6.6% 18/6-close CGC $ 8.750 $ 7.240 -17.3% 14/6-close NZK $ 2.240 $ 2.480 10.7% 4/6-close BUB $ 0.830 $ 0.625 -24.7% 15/5-close SW1 $ 0.410 $ 0.380 -7.3% 14/5-close RHC $ 65.420 $ 55.250 -15.5% 9/5-close FYI $ 0.145 $ 0.115 -20.7% 3/5-close 4DS $ 0.057 $ 0.100 75.4% 2/5-close PME $ 8.150 $ 10.860 33.3% 1/5 TTT $ 1.540 $ 1.590 3.2% 30/4-close CTD $ 24.880 $ 33.540 34.8% 18/4-close CLV $ 1.030 $ 1.575 52.9% 18/4-close VIV $ 0.054 $ 0.043 -20.4% 11/4-close APX $ 8.820 $ 15.010 70.2% 11/4-close BHP $ 29.440 $ 32.385 10.0% 11/4-close PPS $ 0.595 $ 1.135 90.8% 11/4 PTB $ 0.545 $ 0.625 14.7% Return @ 9.53% assuming @ $1k even per stock
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