PYC pyc therapeutics limited

janssen presentation on centyrins

  1. SoT
    858 Posts.
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    http://www.google.com.au/url?sa=t&rct=j&q=&esrc=s&source=web&cd=6&cad=rja&ved=0CEgQFjAF&url=http%3A%2F%2Fwww.cdcat.co.kr%2F%3Fmodule%3Dfile%26act%3DprocFileDownload%26file_srl%3D30982%26sid%3D77cf220d3f3f915e5929b6ff1a649789&ei=a1iqUoDjE8L1kQXwuoHAAw&usg=AFQjCNHsxU7LPEA9oLnGpDcORSNX7t0mtw&bvm=bv.57967247,d.dGI

    This link is to a 21 page Janssen pdf file, titled 'Centyrins' dated June 5th 2013.

    On page 19 the title is 'Intracellular Delivery of Centyrins'. There is a diagram showing a Centyrin attached to a 'Endosomal Escape Peptide' and the following points are shown:
    - Have good evidence that we can get Centyrins into cells and out off endosomes, albeit inefficently
    - Working with an Academic/Biotech consortium to explore methods to improve efficiency

    Comments welcome
    SoT
 
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