phase2b treats both sides so not only double the capsules in the first phase2b group (2x40) vs phase1 but i assume the improvement in pd symptoms, hopefully, will be greater due to treating both sides of the putamen. as is common with pd, up until a point, at least for me, my pd manifested itself on one side first and then gradually progressed onto the other side. i assume the patients are in the study are advanced enough to have symptoms on both sides. so since i haven't much else to do on this rainy morning, i have to think about how just having improvement on 1 side of your body might affect the unified parkinson's disease rating scale - UPDRS. I know when i am tested they have me do movements individually in each limb so i assume the score on the phase1 patients might have been better if both sides of the putamen had been treated. some of the tests are whole body, walking, turning, resisting being pulled backwards, how fast you can rise from a sitting position, can 1 assume not having 1 side of the body treated ( and i have to say i don't know if putting NTCELL only on 1 side only helped improve symptoms on one side and didn't help both sides) possibly give significantly higher (lower the number the better) scores on the movement section of the UPDRS test? i don't know if this has been discussed, if it hasn't been by LCT maybe it's insignificant or maybe it's worth asking someone at LCT?. i know i can't walk/ turn much faster if one leg is rigid and the other isn't.
http://img.medscape.com/fullsize/701/816/58977_UPDRS.pdf
I know people who only have had 1 side of their brain treated for DBS since their symptoms are primarily on 1 side. you can always do a second operation if symptoms progress.
anyway, hopefully 26weeks with both sides treated will give the sig. improvement necessary to get approval with no ambiguity.
- Forums
- ASX - By Stock
- keep in mind that the phase1 trial only treated one side of the putamen
phase2b treats both sides so not only double the capsules in the...
-
-
- There are more pages in this discussion • 1 more message in this thread...
You’re viewing a single post only. To view the entire thread just sign in or Join Now (FREE)
Featured News
Add 1AI (ASX) to my watchlist
|
|||||
Last
0.8¢ |
Change
0.001(14.3%) |
Mkt cap ! $13.49M |
Open | High | Low | Value | Volume |
0.8¢ | 0.8¢ | 0.8¢ | $34 | 4.285K |
Buyers (Bids)
No. | Vol. | Price($) |
---|---|---|
9 | 8215316 | 0.7¢ |
Sellers (Offers)
Price($) | Vol. | No. |
---|---|---|
0.8¢ | 1837858 | 8 |
View Market Depth
No. | Vol. | Price($) |
---|---|---|
9 | 8215316 | 0.007 |
11 | 5066749 | 0.006 |
8 | 6510009 | 0.005 |
4 | 4065000 | 0.004 |
2 | 4590000 | 0.003 |
Price($) | Vol. | No. |
---|---|---|
0.008 | 1837858 | 8 |
0.009 | 1206691 | 9 |
0.010 | 2493145 | 4 |
0.011 | 1490400 | 3 |
0.012 | 363666 | 3 |
Last trade - 10.00am 04/09/2024 (20 minute delay) ? |
Featured News
1AI (ASX) Chart |