Key Point., page-21

As I mentioned on the other thread a few moments ago, many brokers/instos will sell even before an announcement. To hold through (like us mug punters) is simply a gamble for them.
If you bought x million shares in recent CR, you sell at a profit and liquidate you risk. It's simple.
Today's ann gave them a great opportunity to do this whilst remaining in the money. Beautiful.

On another note, remember this was a Phase I trial (ok, actually upgraded to a IIa) so there is nothing FA wise that can be considered disappointing IMO (with the exception that the cancer has not been fully exterminated and the participants have not yet flown out the window to crap money on the peasants below as some investors had hoped)