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https://finance.yahoo.com/news/nektar-bristol-myers-end-clinical-...

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onesurfed

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19/04/22

07:44

Post #: 60901395
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Originally posted by onesurfed: ↑

Here's a comment from a competing website where the author originally misspelled "Bempeg" as "Bemped". (what an idiot)
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"Turning cold tumor "hot" is one objective of EVT801. That's basically the same thing objective that the now-discarded Bemped had. Bad news for Nektar is good news for Kazia, the way I see it. From Cancer Discovery (2020): "As low tumor PD-L1 expression, low levels of baseline tumor-infiltrating lymphocytes (TIL), and absence of a T-cell inflamed tumor microenvironment can be associated with a poor response to CPI (7–10), novel therapeutic approaches that stimulate T cells or overcome T-cell exhaustion may complement or synergize with checkpoint inhibition to achieve durable responses for more patients."
So that was the rationale for Bemped trials. I feel for Nektar investors, but maybe they'll now be made aware of EVT801 and Kazia."
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(Bempeg was being trialed with the checkpoint inhibitor Opdivo and the trials have now been quit by BMY.)

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https://finance.yahoo.com/news/nektar-bristol-myers-end-clinical-204205857.html
https://finance.yahoo.com/m/8ae64bd8-069b-3bda-92e7-d571b0a72cc4/nektar-therapeutics-stock.html
https://aacrjournals.org/cancerdiscovery/article/10/8/1158/2710/Bempegaldesleukin-NKTR-214-plus-Nivolumab-in
https://stockcharts.com/h-sc/ui

That's some background for my previous post about a guy's comments on Nektar. Apparently Bempeg was being trialled with Keytruda and Opdivo individually.

I've got a question for the audience here, and that is "Does anyone remember what checkpoint inhibitor EVT801 was used with in the preclinical trials which showed such synergy?"

KZA Price at posting: $1.13 Sentiment: Buy Disclosure: Held
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https://finance.yahoo.com/news/nektar-bristol-myers-end-clinical-...

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