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KZA Media Thread, page-1939

  1. 2,072 Posts.
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    From upcoming presentation by Dr. Wen:
    " For the overall ITT population, the median progression free survival was 8.4 months (RANO) and 8.6 months (mRANO) and the median overall survival was 15.7 months. In a mITT (n = 22 patients treated with 60mg daily and ≥1 post-baseline assessment), the median PFS was 9.6 months (mRANO)."
    ..............
    While there can be positive bias in mITT analyses, 8.6 months mRANO is good to see, especially considering there could be a strong correlation between mRANO PFS and OS, as there was in this particular study of another agent:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8282697/



 
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