Hi all I believe this is my first post but I have spent years reading post concerning PRR.The question being asked is
"Why will they test CVAC on other cancer indications
From Prima website
At Prima BioMed the tumour antigen being targeted is called mucin-1. This is a molecule expressed by a variety of tumours including breast, ovarian, prostate, lung and colon cancers. Mucin-1 is expressed by normal tissue in the body but changes conformation on tumour cells so the immune response will be specific to the tumour tissue and will not damage normal tissue. We also use a proprietary immune adjuvant called mannan (oxidised mannose). Mannan assists in activating the immune system and ensures preferential expression of the production of killer T cells that will target mucin-1.
Makes sense to me that if it doesnt work on ovarian cancer then it wont work on the above cancer types also expressing mucin- 1..
So why waste time on other cancers...unless of course they know it works for ovarian and will have similiar results for
other cancer types...Just they way I look at it.
Sung
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