According to the paper below long Covid patients have amyloid...

According to the paper below long Covid patients have amyloid deposits in their muscles. In 2017 Prana was associated ( Dr. R Cherny) with an Italian group when studying Cardiac amyloidosis and PBT2 helped treat this in an animal model. Prana even patented PBT2 for this purpose.

The paper with the Italian group is: Cardiac Light Chain Amyloidosis: The Role of Metal Ions in Oxidative Stress and Mitochondrial Damage.

Now I believe that PBT2 is licensed to Prof. Masters also in this my hypothetical indication for PBT2. We know that Masters is interested in very early Alzheimers disease. I would say that a COVID infection could be the very timepoint when alyloidosis production all over the body including brain will activate and so it could well be the time point Masters is interested ????

Here is this new paper: https://www.nature.com/articles/s41467-023-44432-3




Muscle abnormalities worsen after post-exertional malaise in long COVIDBrent Appelman, Braeden T. Charlton, Richie P. Goulding, Tom J. Ke et all

Abstract

A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months after infection. A distinctive symptom of patients with long COVID is post-exertional malaise, which is associated with a worsening of fatigue- and pain-related symptoms after acute mental or physical exercise, but its underlying pathophysiology is unclear. With this longitudinal case-control study (NCT05225688), we provide new insights into the pathophysiology of post-exertional malaise in patients with long COVID. We show that skeletal muscle structure is associated with a lower exercise capacity in patients, and local and systemic metabolic disturbances, severe exercise-induced myopathy and tissue infiltration of amyloid-containing deposits in skeletal muscles of patients with long COVID worsen after induction of post-exertional malaise. This study highlights novel pathways that help to understand the pathophysiology of post-exertional malaise in patients suffering from long COVID and other post-infectious diseases.

I am posting this as speculation. I have nothing more to support my hypothesis.