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"Cryo-VaccTM is ideal for both air and ground transportation,...

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    "Cryo-VaccTM is ideal for both air and ground transportation, utilising liquid nitrogen to transport by
    road and helium to transport by air
    .
    Aside from helium being only a fraction of the weight of
    nitrogen,significantly reducing its cost in airfreight, when used in Cryo-VaccTM helium can
    accommodate up to 12 times more vials per flight compared to other cryogens based on current
    flight safety regulations."

    ASX ann Cryo-Vacc launch

    From a post of mine earlier today
    "Companies and investors are pouring money into innovating and enhancing cold chain infrastructure to get the COVID-19 vaccine around the world. UPS, for one, has constructed "freezer farms" — banks of ultra cold chain freezers — in Louisville, Ky. and the Netherlands, where it plans to store millions of vaccines at subzero temperatures. From there, the company plans to ship the shot worldwide."

    All my highlights.

    Apart from south Africa and its particular needs I would suggest that air transport could be the end target

 
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