Looks like we on the move, page-44

“The baseline NRS pain score prior to treatment with PPS was a high score of 7. Patient was administered by subcutaneous injection a dose of 150 mg fixed dose of PPS twice weekly for 4 weeks (ie a total of 8 injections). The patient experienced improvement in pain soon after the 4th injection and after the 8th injection (completion of treatment) experienced a significant reduction in pain recording a low NRS pain score of 2 to 3. During the course of the treatment the patient had abstained from any other therapeutic intervention. No adverse events were experienced during and after the course of PPS treatment. In further work, a dosing and treatment regimen of 2 mg/kg PPS or a fixed dose of 150mg administered by slow SC injection twice-weekly for 6 weeks surprisingly gave consistent resolution of Modic Changes as assessed by magnetic resonance imaging.”


scratch what I thought.....they are already investigating CLBP with PPS.....