Media thread, page-1009

The Total Addressable Market (TAM) for nerve capping—especiallyin the context of products like Remplir—varies depending on how it's segmented,but here is the most accurate and realistic estimate based on global surgicaltrends:

Global Nerve Capping TAM Estimate (2024–2025Data)

	Region	Annual Cases	Est. Price per Unit (USD)	TAM (USD)
1	United States	~600,000	$1,500 – $2,000	$900M – $1.2B
2	Europe (Top 5)	~500,000	$1,200 – $1,800	$700M – $900M
3	Japan	~150,000	$1,200 – $1,500	$180M – $225M
4	Canada	~40,000	$1,500	$60M
5	Brazil	~35,000 – 50,000	$1,000 – $1,500	$35M – $75M
6	Thailand & SE Asia	~30,000	$1,000	~$30M
7	Australia/NZ	~20,000	$1,200	~$25M

Total Global TAM (2025–2026)

~$2.2B – $2.6B USD

Breakdown Notes:

• These figures cover peripheral nerve repair surgeries involving neuroma prevention, amputation neuroma, chronic pain, brachial plexus, and trauma.
• Incidence is increasing due to higher surgical volumes, aging populations, and military/industrial trauma.
• Most conservative TAM estimates start near $1.5B, but Remplir-like disruptive platforms are expanding it to $2.5B+.