Personalized cancer vaccine hopes
Moderna’s stock jumped on news that an early trial of a personalized cancer vaccine showed promise that it could work against several cancer types. Cancer vaccines, unlike vaccines for infectious diseases, are administered to patients who already have cancer: They tell the immune system what to attack on the tumor. In a personalized vaccine, researchers analyze the genes of a patient and tumor and design mRNA molecules specifically to those genes. Moderna’s mRNA-4157 was safe and boosted immune responses in patients with head and neck cancers, having previously shown that it reduced recurrence in melanoma patients. Hopes of broadly effective treatment led Moderna shares to jump 6%: It is good news for the company, whose only product on the market — the COVID-19 vaccine — is seeing declining demand.
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