Media Thread, page-13922

Interesting article published in Nature.com The Chinese have tested an OV and T cell combo and an OV and mRNA combo in tumor treatment in mice, it was published 03/05/2024 is limited in the cancer types for trial but as the conclusion states OV with T cells is very promising. OASIS is way in front of this trial, but it does show promise and increased efficacy over OV's alone, enjoy the read, poses the question might IMU look at mRNA tech next?

bit sciency but some here will enjoy.

In conclusion, our study demonstrated that the combination therapy with oncolytic virus and adoptively transferred T cells could amplify their antitumor effects, we also shed light on the mechanisms through which OVs enhance the antitumor efficacy of adoptively transferred T cells, which might provide valuable insights into its potential clinical applications. Notably, we proposed that the administration of mRNA vaccines in combination with OVs holds promise as an effective therapeutic strategy for solid tumors.

Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects | Signal Transduction and Targeted Therapy (nature.com)