@MrLearnerI think this is a good question. I am no means an...

@MrLearner

I think this is a good question. I am no means an expert but the impression is artificial bile duct engineering is very complex. A couple of factors to consider appear to be:

- Extensiveness of the damage caused by the bile duct cancer (ie how much of the liver and other parts of the body are affected).
- The corrosiveness of bile, hence how to contain it safely without damaging other organs, and how to regulate the volume of bile (ie mimic the valve).

I think quality of life is also important. IMU's approach appears to be shrinking the tumour using a combination of techniques and being able to keep most of the original tissue and support a healing process, would be the ideal case for a person in remission live a best possible life.

That is why the descriptive and diagnostic data from the IMU clinical trials will be so important. Imagine finding out the bad news of having a solid tumour cancer, and then learning that the catalyst for remission is a potential gold standard treatment involves something resembling a vaccination shot.