IMM 3.57% 43.5¢ immutep limited

Bell Potter update Couple of snips "Efti continuing trials...

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    Bell Potter update

    Couple of snips

    "Efti continuing trials across 5 oncology indications.
    By the end of CY2024, Immutep are expected to be conducting a global Phase 3 trial
    in non-small cell lung cancer (NSCLC) following the highly impressive data that was
    published from Phase 2 trials in 2023. This indication continues to be the key focus for
    IMM and will likely be the largest use of funds over the next ~2 years (currently $104m
    cash at bank).
    The next major readout catalyst for IMM is first data from the Phase 2b trial in head
    and neck cancer (TACTI-003, n=171). We expect data will be announced in Q2 CY24.
    This will be the first time the efti + Keytruda combo will be evaluated head-to-head
    against Keytruda in a two-arm trial. The primary endpoint is response rate (ORR), with
    typical secondary efficacy endpoints such as overall survival (mOS), progression-free
    survival (mPFS) and duration of response (DoR).
    Additional Phase 1 and Phase 2 trials are ongoing with efti in breast cancer, soft tissue
    sarcoma, and urothelial carcinoma. Beyond efti, IMP761, the LAG-3 agonist for
    autoimmune diseases, will begin its first Phase 1 clinical trial in mid-CY24."

    "Investment view: Buy (speculative), Valuation $0.65.
    We have rolled forward our DCF model for time creep and made no other changes to
    our valuation assumptions, which is based on risk-adjusted licensing income from efti
    in NSCLC, head & neck cancer, and metastatic breast cancer indications. As a result,
    our valuation is increased to $0.65 per share (from $0.55) and we maintain our BUY
    (speculative) recommendation."
 
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