Medical uses Discussion

Thought a thread on Medical use and in particular evidence might be on interest
GW Pharma has bagged a landmark approval for its cannabinoid Epidyolex, with European regulators clearing its use for the treatment of seizures in patients with two rare, severe forms of childhood-onset epilepsy.

This sounded better than most trials I have looked at

"The European Commission approved the drug's use as adjunctive therapy of seizures associated with Lennox Gastaut syndrome (LGS) or Dravet syndrome, in conjunction with clobazam, for patients two years of age and older, paving the way for its launch across Europe.

More than 90% of patients with LGS or Dravet syndrome have multiple seizures per day, which puts them at constant risk for falls and injury.

The drug's clearance rides on the back of results from four randomised, controlled Phase III trials, incorporating data from more than 714 patients with either condition, both of which remain highly treatment-resistant despite currently available therapies.

When added to other antiepileptic therapies, Epidyolex “significantly reduced the frequency of seizures in patients,” according to GW Pharma."