Not sure if you guys have seen this but here it is anyway. You might need to register to see it, but it's free access. I've included a few snippets from it.
Low Testosterone Associated With High Mortality in Men With CHD
"October 27, 2010 ? Among men who have coronary heart disease, mortality was doubled in those with low testosterone levels compared with those who had normal levels, a new observational study has shown. Dr Chris J Malkin (Royal Hallamshire Hospital, Sheffield, UK) and colleagues report their findings in Heart."
"This is the fourth epidemiologic study to have shown that low testosterone is a marker of early mortality," senior author Dr Kevin S Channer (Royal Hallamshire Hospital, Sheffield, UK) told heartwire . "But most crucially, it is the first in men with vascular disease; all of the other epidemiologic follow-up studies of testosterone have excluded this patient population."
"Channer explains that testosterone replacement therapy can be given in a number of ways. Testosterone is not suitable for oral therapy, because "It undergoes high first-pass metabolism through the liver," he explains. But it is available in slow-release injection formulations, as a three-month depot injection, as transdermal patches, and as a gel. He says his team has had some problems with the skin patch because it causes a rash and men tend not to like it, but they have had more success with the three-month depot injections, which they have been able to keep people on for a year. However, "We desperately need some other formulations," he says."
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