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prana’s u.s. capital approved by australian shareh

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    COMPANY ANNOUNCEMENT
    Prana’s U.S. capital approved by Australian shareholders
    Melbourne, Australia – 2 June, 2004: Shareholders in Prana Biotechnology Limited
    (NASDAQ: PRAN, ASX: PBT) have approved the issuing of securities worth US $20
    million to institutional and professional investors, led by New York-based global
    healthcare fund managers, OrbiMed Advisors and XMark Funds. The transaction was
    originally announced on April 28, 2004.
    Geoffrey Kempler, Executive Chairman of Prana commented: “This substantial support
    shown by leaders in the healthcare investment community reflects the progress and
    strength of Prana’s technology.
    “With this offering, we have been able to enhance shareholder value by increasing our
    access and exposure to the vast US capital markets and br oaden our base of US
    institutional investors, complementing our traditional Australian shareholder base.
    “We continue to build on our already strong connection with the US and now have a
    board member, Dr Jon Alsenas, and our chief scientist (one of the inventors of our
    MPAC technology) Prof Ashley Bush, based there. This capital raising will provide the
    funds to progress PBT-2, our proprietary MPAC for Alzheimer’s disease, into clinical
    trials in Australia through 2005 and 2006,” said Mr Kempler.
    Investors also purchased five-year warrants to purchase an additional 3 million ADR’s at
    an exercise price of US$8.00 per ADR. If exercised, this would raise an additional
    US$24 million for the Company. Investment bank, Rodman & Renshaw LLC acted as the
    placement agent for the transaction.
    ENDS
    About Prana’s technology
    PBT-1 and PBT-2 are Metal Protein Attenuating Compounds or MPACs. Prana’s MPACs are chemicals that
    bind zinc and copper, and have been shown to lower the levels of amyloid beta (and associated toxicity) in
    the brains of transgenic mice used as a model of Alzheimer’s Disease.
    About Prana
    Prana is a Melbourne-based biotechnology established in 1997 to commercialize research into Alzheimer's
    disease and other major age-related degenerative disorders (Nasdaq: PRAN; ASX: PBT). Prana's
    technology was discovered by the company's researchers at prominent international institutions including Dr
    Ashley Bush and Dr Rudy Tanzi at the Massachusetts General Hospital at Harvard Medical School and
    Professor Colin Masters at the University of Melbourne. For more information about Prana, please visit
    www.pranabio.com
    For more information contact:
    Company Media and Investor, US Media, Australia
    Geoffrey Kempler, Prana Ivette Almeida and Steven Silver Kate Mazoudier
    +61 (3) 9690 7892 212-983-1702 ext. 209 and 212 +61 3 9866 4722
    [email protected] [email protected]
    [email protected]
 
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