Overall, mice and humans share virtually the same set of genes. ... Of the approximately 4,000 genes that have been studied, less than 10 are found in one species but not in the other. Both the mouse and human genomes contain about 3.1 billion base pairs (or chemical letters)
As a minimum requirement, mice used in experiments must be of the same purebred species. Another reason rodents are used as models in medical testing is that their genetic, biological and behavior characteristics closely resemble those of humans, and many symptoms of human conditions can be replicated in mice and rats
Overall, mice and humans share virtually the same set of genes....
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