This article https://www.researchgate.net/publication/323936098_Manufacturing_human_mesenchymal_stem_cells_at_clinical_scale_process_and_regulatory_challenges is 2 years old.
The field is rapidly changing and evolving. The conclusion in the article certainly doesn't suggest MSB has an emergency on it's hands. Challenges? Maybe.
But a few points.
- As has already been stated by another poster the form of Ryoncil/remestemcell-L now being used is an improved version.
- The recommendations they've made are likely to already be on SI's radar.
- The financing for manufacturing scale up has only just occurred.
- The approval process is being fast tracked in the Covid-19 environment.
Other than that, nice try.
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