Over the course of the reformulation program, tesa Labtec produced over 200 different variants of the TPM®/Oxymorphone patch to ensure they identified the optimal composition. The most promising of these new TPM®/Oxymorphone patches has increased transdermal flux in-vitro compared to the previous clinical patch, as well as enhanced physical and chemical stability across a range of standard stress tests. The performance of the patch in these assessments met or exceeded Phosphagenics’ expectations towards a commercial product. Importantly, the reformulation program produced TPM®/Oxymorphone patches appropriate for commercialisation in either the Japanese or US market. These TPM®/Oxymorphone patches have now been submitted for final stability assessments.
the jap 1 day patch didn't cut the mustard, but the 72 hr patch is set to go...a good payout from mylan may see us embark on a ph 2...if a US partner cant be found
Mylan arbitration, page-290
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