Hotcopper tends to destroy your formatting when you post. Have tried to repost the tables I included below in a more readable format.
Hashan's POS from Table 4 of his article
Phelan-McDermid:
Phase III
30%
1 Angelman:
Phase II
15%
2 Pitt-Hopkins:
Phase II
15%
3 Prader-Willi:
Phase II
10%
Comparing patient numbers from Hashan vs Neuren.
Hashan
Neuren
1 Phelan-McDermid
40k
24k
2 Angelman
27k
19k
3 Pitt-Hopkins
29k
6k
4 Prader-Willi
32k
17k
Comparing POS from Hashan vs published research.
Phase
Table 4
90-95% disc
Wong et al (2019) MIT
1 Phelan-McDermid
Phase III
30%
5%-10%
32%
2 Angelman
Phase II
15%
5%-10%
8.3%
3 Pitt-Hopkins
Phase II
15%
5%-10%
8.3%
4 Prader-Willi
Phase II
10%
5%-10%
8.3%
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