I was reading this sort of thing when i got the idea that...

I was reading this sort of thing when i got the idea that peptidream are also interested in drugging tthe undrugable. From https://www.japantimes.co.jp/news/2...molecules-bring-new-tool-pharma/#.WqCvhtA7a7M

Quote of part of the above "Not only that, PeptiDream kept part of its discovery for itself. Its system can create three types of drugs — peptide therapeutics, small-molecule medicines and what’s called peptide drug conjugates. The first is mostly used for extracellular medicines, while the second, which are smaller, can permeate the cell. PeptiDream’s partnerships cover only those two.

The third, PDCs as they are called, are envisaged as a kind of smart drug. The peptide part will be used, for example, to home in on a cancer cell, which the conjoined drug will then attack. This contrasts with conventional treatments such as chemotherapy that kill other cells as well as the cancerous ones, resulting in hair loss, nausea and other symptoms. Reid and his team are focusing on this area within the company.

“We carved that out,” Reid said. “The market is growing very rapidly. It’s one of the most rapidly growing areas of therapeutics.”  "



I would be interested in how they propose to target cancer cells. It has been brought up before by bioexec i believe that one proplem with intra venous use of peptides is the sink effect, in that the cell penetrating peptides are absorbed by all cells they contact?? The original point made on omomyc trials with pyc peptides i believe was that fpp/omomyc could be absorbed by all cells, but only seemed to have a destructive or restrictive effect on cancerous growing cells. Minor and reversible side effects on healthy cells. Seems the true miracle would be to discover a fpp that can indeed target a particular cell type. I get the idea that may still be a long way off for both pyc and peptidream?

There are so many crossing storylines here as we also have the recent reports of cancer immunology treatment which could be injected into cancer tumors and would then spread to search and destroy other seperate tumors of same type?