"Outside clinical trials, the first COVID‐19 vaccine was administered on 8 December 2020. Researchers aimed to quantify the global impact of the first year of COVID‐19 vaccination programmes using mathematical modelling to fit COVID‐19 transmission and vaccination to reported COVID‐19 mortality and all‐cause excess mortality in 185 countries and territories.1They determined the number of lives lost if there had been no vaccines. Based on reported COVID‐19 deaths, vaccinations prevented an estimated 14.4 million deaths (95% credible interval [Crl] 13.7–15.9) from COVID‐19 in a year. However, if excess deaths were used, this estimate rose to 19.8 million (95% Crl 19.1–20.4) deaths prevented (Fig. 1), equating to a global reduction of 63% in total deaths (19.8 million of 31.4 million) during the first year of COVID‐19 vaccination." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537923/
