Yes Terrapower Isotopes is producing AC225 and I reckon this is where Silex will get it's AC225 to get Yb-176 to enrich, the key pre-cursor for the production of Lutetium-177.
TerraPower has a unique Ac-225 manufacturing process that has the potential to provide the scale and dependability needed for commercial manufacturing at a purity level appropriate for clinical us.
“The new beta-particle therapies, such as Cu-67 and Lu-177, with their favourable energy characteristics and path lengths, are revolutionising the radiopharmaceutical space because of their proven efficacy and excellent safety profiles compared to many other beta and alpha emitting isotopes. The small number of commercially available targeted radiopharmaceutical therapies all use beta emitting isotopes, and they represent the best opportunity to significantly change the treatment paradigm with the potential for much earlier stage treatments and in combination with standard of care treatments or immuno-oncology products. Novartis, the current leader in radiopharmaceuticals, has cornered much of the Lu-177 supply market, given the precarious supply chain of Lu-177 and reliance on a limited number of aging nuclear reactors, inhibiting new companies from entering this space.
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